
DUAC Topical Gel contains the antibiotic clindamycin. You should not use DUAC Topical Gel if you: are allergic to benzoyl peroxide or the antibiotics clindamycin or lincomycin, have Crohn’s disease, have ulcerative colitis, or have developed inflammation of the colon (colitis) with past antibiotic use.
Clindamycin taken orally or through IV may result in severe colitis, which may result in death. Topical clindamycin has been shown to be absorbed through the skin and may reach the bloodstream. Diarrhea, bloody diarrhea, and colitis have been reported with the use of topical clindamycin. If you experience any of these signs, stop DUAC Topical Gel and call your doctor immediately.
DUAC Topical Gel is for skin use only; avoid contact with the eyes and mucous membranes. If you use DUAC Topical Gel with other topical acne medications, skin irritation may result.
Antibiotics may result in an overgrowth of bacteria and other living organisms. If you develop a yeast infection, stop using DUAC Topical Gel and call your doctor.
DUAC Topical Gel should not be used with products that contain erythromycin. Tell your doctor if you take medicine containing erythromycin.
Tell your doctor if you are pregnant or plan to become pregnant, as it is not known if DUAC Topical Gel may harm your unborn baby.
It is not known if DUAC Topical Gel passes into breast milk. Topical clindamycin may be absorbed through the skin into the bloodstream. Clindamycin may pass into the breast milk when taken by mouth or by injection. You and your doctor should decide if you will use DUAC Topical Gel or breast-feed.
It is not known if DUAC Topical Gel is safe or effective in children under 12 years of age.
In medical studies, side effects of DUAC Topical Gel were generally limited to the skin and included peeling, dryness, burning, and/or redness.
If you develop allergic symptoms such as severe swelling or shortness of breath, you should stop using DUAC Topical Gel and contact your doctor immediately.
DUAC Topical Gel may bleach hair and colored fabrics.
Avoid long periods of time in sunlight. Always wear sunscreen and wear a hat or other clothing to decrease your exposure to the sun.
For more information about DUAC Topical Gel, read the Full Prescribing Information.