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DUAC Gel contains the antibiotic clindamycin. You should not use DUAC Gel if you: are allergic to benzoyl peroxide or the antibiotics clindamycin or lincomycin, have Crohn’s disease, have ulcerative colitis, or have developed inflammation of the colon (colitis) with past antibiotic use.
Clindamycin taken orally or through IV may result in severe colitis, which may result in death. Topical clindamycin has been shown to be absorbed through the skin and may reach the bloodstream. Diarrhea, bloody diarrhea, and colitis have been reported with the use of topical clindamycin. If you experience any of these signs, stop DUAC Gel and call your doctor immediately.
DUAC Gel is for skin use only; avoid contact with the eyes and mucous membranes. If you use DUAC Gel with other topical acne medications, skin irritation may result.
Antibiotics may result in an overgrowth of bacteria and other living organisms. If you develop a yeast infection, stop using DUAC Gel and call your doctor.
DUAC Gel should not be used with products that contain erythromycin. Tell your doctor if you take medicine containing erythromycin.
DUAC Gel may bleach hair and colored fabrics.
Avoid long periods of time in sunlight. Always wear sunscreen and wear a hat or other clothing to decrease your exposure to the sun.
Tell your doctor if you are pregnant or nursing. DUAC Gel should be given to a pregnant or nursing woman only if clearly needed.
It is not known if DUAC Gel is safe or effective in children under 12 years of age.
In medical studies, side effects of DUAC Gel were generally limited to the skin and included peeling, dryness, burning, and/or redness.
If you develop allergic symptoms such as severe swelling or shortness of breath, you should stop using DUAC Gel and contact your doctor immediately.
For more information about DUAC Gel, read the full Prescribing Information.